Full Text PA-97-028 INDIVIDUAL POSTDOCTORAL AND SENIOR FELLOWSHIPS IN GENOMIC ANALYSIS AND TECHNOLOGY AND THE ETHICAL, LEGAL AND SOCIAL IMPLICATIONS OF HUMAN GENETICS RESEARCH NIH GUIDE, Volume 26, Number 3, January 31, 1997 PA NUMBER: PA-97-028 P.T. 22 Keywords: Human Genome Genetics Ethics/Values in Science & Technol National Center for Human Genome Research Application Receipt Dates: April 5, August 5, December 5 PURPOSE This is a reissue of a Program Announcement that appeared in the NIH Guide for Grants and Contracts. Vol 20, No. 46, December 12, 1991. Scientists and scholars who are well-trained in one or more of a variety of disciplines will be needed to accomplish the goals of the National Center for Human Genome Research (NCHGR) research program and to use, for further research, the resources that the program will develop. Therefore, the NCHGR is offering both individual postdoctoral fellowships and senior fellowships to highly qualified individuals who are seeking training that will enable them to engage in research relevant to the genome project. Broad areas of research that are relevant include genomic analysis (including technology development) and the ethical, legal, and social implications of human genetics research. The NCHGR is interested in supporting fellowship training in both broad areas. HEALTHY PEOPLE 2000 The Public Health Service (PHS) is committed to achieving the health promotion and disease prevention objectives of Healthy People 2000, a PHS-led national activity for setting priority/areas. This program announcement is related to several priority areas affecting human health, including cancer, heart disease and stroke, diabetes and chronic disability conditions, maternal and infant health, and others. Potential applicants may obtain a copy of "Healthy People 2000" (Full Report: Stock No. 017-001-00474-0 or Summary Report: Stock No. 017-001-00473-1) through the Superintendent of Documents, Government Printing Office, Washington, DC 20402-9325 (telephone 202-512-1800). ELIGIBILITY REQUIREMENTS Only U.S. citizens or permanent residents of the United Stated are eligible for NRSA support. Before an NRSA award can be activated, the individual must have received a doctoral degree to be eligible for an individual postdoctoral fellowship (F32). To be eligible for a senior fellowship (F33), individuals must have received, as of the beginning date of the NRSA appointment, a doctoral degree and must have had at least seven subsequent years of relevant research or professional experience. Individuals who have had a hiatus in their research career may also apply for an NRSA fellowship to develop skills or to update their knowledge in a particular area. Applications from women, minorities and individuals with disabilities are especially encouraged. MECHANISM OF SUPPORT Support for F32 and F33 fellowships will be provided through the National Research Service Award (NRSA). The stipend levels for the individual postdoctoral fellowships range from $20,292 to $32,300 depending on the number of years of relevant experience subsequent to the award of the doctoral degree. The stipend level for senior fellowships is $32,300 per annum. Beginning with competing postdoctoral fellowships awarded in fiscal year 1997, the NIH will provide an institutional allowance of $4,000 per 12-month period to non-federal, non-profit sponsoring institutions to help defray such awardee expenses as self-only health insurance, research supplies, equipment, and travel to scientific meetings. The NIH will provide up to $3,000 for fellows sponsored by Federal laboratories or for-profit institutions for expenses associated with self-only health insurance, travel to scientific meetings, and books. The NIH also will provide additional funds to offset the combined cost of tuition and fees for specific courses, which support the research training experience, at the following rate: 100 percent of all costs up to $2,000 and 60 percent of costs above $2,000. Individuals may receive up to three years of aggregate NRSA support at the postdoctoral level, including any combination of support from institutional training grants and individual fellowship awards. Exceptions to the three-year limit require a waiver from the awarding unit. Individuals interested in a waiver should consult with staff of the awarding unit. Recipients of National Research Service Awards are subject to payback provisions. Details about this requirement and the policies governing this program can be found in the National Research Service Awards Guidelines (see NIH Home Page; URL is: http://www.nih.gov/grants/oep/f32.htm). Single copies are also available from this office. RESEARCH OBJECTIVES The mission of the National Center for Human Genome Research (NCHGR) is to characterize the human genome and the genomes of selected model organisms. The NCHGR's research program began in 1990 with an initial set of goals which were updated in 1993. The most recent goals are discussed in FS Collins and D Galas, "A New Five-Year Plan for the U.S. Human Genome Project", Science, 1993; 262:43-46. Significant progress has been made in the past six years, with some goals, (e.g., the genetic linkage maps of the human and mouse, the initial goals of the Ethical, Legal, and Social Implications Program), having been achieved on or ahead of schedule Other goals,(e.g., physical maps of the human and mouse, complete DNA sequence of the genomes of several important non-human organisms), are expected to be met in the next one to two years, while the final goal initially set out for the Human Genome Project, the complete sequence of human DNA, is expected to be achieved by the year 2005, as originally set forth. Additional information about the National Center for Human Genome Research and its research interests can be found on the NCHGR Home Page; the URL is: http://www.nchgr.nih.gov. The goal of the Fellowship Program in the area of genomic analysis and technology is to train highly skilled scientists who will use the expertise gained to develop research programs in the mapping and sequencing of the human genome and the genomes of other organisms, in the analysis and interpretation of the resulting data, and in the development of biological, medical or biotechnological applications based on the data, or in technologies to support any of this research. The goal of the Fellowship Program in the area of ethical, legal and social implications of human genetics research is to increase the number of scholars who are knowledgeable in both genomic science and in social science, law, or philosophy and who are interested in examining the ethical, legal and social implications of human genetics research. The NCHGR will support fellowship training for: o molecular biologists and geneticists who wish to receive additional training in genomic analysis or other technical areas relevant to genome research; o non-biologists, such as those with degrees in the mathematical, physical, chemical, engineering, and/or computer sciences, who wish to obtain training in molecular biology or genetics in order to pursue interdisciplinary approaches to genome studies; o scientists with training in biology, mathematics, computer science or other relevant areas who wish to obtain training (or additional training) in bioinformatics or computational biology; o scientists and health professionals who wish to obtain training that will allow them to address the ethical, legal and social implications (ELSI) of human genetics research; and o scholars trained in the humanities who wish to receive training in genomic or genetic research in order to pursue studies in the ELSI area. The F32 mechanism is used to support research training for individuals who wish to receive in-depth training in genomic research. Moreover, an individual who has already completed one postdoctoral fellowship in another scientific discipline may be eligible for a postdoctoral fellowship in genomic research, if the additional training can be justified in terms of the individual's future commitment to pursuing a career in genomic research. Similarly, an individual who has already completed one postdoctoral fellowship in a humanities discipline may be eligible for a postdoctoral fellowship in ELSI research, if the additional training can be justified in terms of the individual's future commitment to pursuing a career in the ELSI aspects of human genetics. The F33 mechanism is designed to provide research training for scientists or scholars who are at least seven years beyond their doctoral degree and who wish to update their skills or pursue new areas of research. APPLICATION PROCEDURES Applications are to be submitted on the grant application form PHS 416-1 (rev. 8/95). Three letters of recommendation must accompany the application. Application kits are available from most institutional offices of sponsored research and from the Division of Extramural Outreach and Information Resources, National Institutes of Health, 6701 Rockledge Drive, MSC 7910; Bethesda, MD 20892-7710, telephone (301) 710-0267, email: ASKNIH@odrockm1.od.nih.gov. All individual fellowship applications are on an expedited review schedule. Receipt dates for applications are April 5, August 5, and December 5 annually. The original and two copies of the application must be submitted to: DIVISION OF RESEARCH GRANTS NATIONAL INSTITUTES OF HEALTH 6701 ROCKLEDGE DRIVE, ROOM 1040, MSC-7710 Bethesda, MD 20892-7710 Bethesda, MD 20817 (for express/courier service) The earliest dates that awards can be made are September, January, and May, respectively. REVIEW CONSIDERATIONS Applications submitted in response to this program announcement will be reviewed in accordance with the usual NIH peer review procedures. The following factors are considered in the review of fellowship applications: (1) the candidate's potential for a research career; (2) the scientific or scholarly merit and training potential of the research proposal; (3) the training environment and resources; and (4) the protections accorded human subjects and vertebrate animals. The second level or review is performed by the appropriate oversight group of the NIH awarding component. AWARD CRITERIA The following criteria will be used in making awards: the quality of the training experience, the relevance of the training to the awarding units goals; and the availability of funds. INQUIRIES Written and telephone inquiries concerning this program announcement are encouraged. The opportunity to clarify any issues and questions from potential applicants is welcome. Direct inquiries regarding programmatic issues to the following staff: Individual and Senior Fellowships in Genomic Analysis and Technology: Bettie J. Graham, Ph.D. Division of Extramural Research National Center for Human Genome Research Building 38A, Room 614 Bethesda, MD 20892-6050 Telephone: (301) 496-7531 Email: Bettie_Graham@nih.gov Individual and Senior Fellowships in ELSI topics: Eric M. Meslin, Ph.D., Director Ethical, Legal, and Social Implications Research Program National Center for Human Genome Research Building 38A, Room 617 Bethesda, MD 20892-6050 Telephone: (301) 402-4997 Email: Eric_Meslin@nih.gov For information about PHS Grant Policy, applicants may contact: Ms. Jean Cahill Grants and Contracts Management Branch National Center for Human Genome Research Building 38A, Room 613 Bethesda, MD 20892-6050 Telephone: (301) 402-0733 Email: Jean_Cahill@nih.gov AUTHORITY AND REGULATIONS This program is described in the Catalog of Federal Domestic Assistance No. 93.172. Awards will be made under the authority of Public Service Act, Title IV, Part A (Public Law 78-410, as amended by Public Law 99-158, 42 USC 241 and 285) and administered under PHS grants policies and Federal Regulations 42 CRF 52 and 45 CRF Part 74. This program is not subject to the intergovernmental review requirements of Executive Order 12372 or Health Systems Agency review. The PHS strongly encourages all grant and contract recipients to provide a smoke-free workplace and promote the non-use of all tobacco products. In addition, Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking in certain facilities (or in some cases, any portion of a facility) in which regular or routine education, library, day care, health care or early childhood development services are provided to children. This is consistent with the PHS mission to protect and advance the physical and mental health of the American people. .
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