OPERATION AND MAINTENANCE OF A CHIMPANZEE BREEDING COLONY

Release Date:  April 27, 1999 

Source Sought For Proposals

P.T.

National Institute of Allergy and Infectious Diseases

The National Institute of Allergy and Infectious Diseases (NIAID), Division of
Intramural Research, seeks Capability Statements from qualified sources for
the purpose of providing on loan to the NIAID approximately 10 hepatitis and
respiratory syncytial virus free infant chimpanzees (Pan troglodytes) annually
for hepatitis, respiratory virus, and other infectious disease research and
vaccine development. It is expected that the operation of a chimpanzee
breeding colony will be necessary for this provision of infant chimpanzees.

Any Offeror shall possess, or be able to acquire, all necessary personnel,
housing, facilities, and equipment to adequately care for the breeding
chimpanzees and progeny. The animal facilities provided must be of such design
to insure isolation from other animals known or suspected to be infected with
any hepatitis virus or other infectious agent or any other common primate
infection such as tuberculosis. Upon termination of studies utilizing
chimpanzees, the Government will return same to Any Offeror. Any Offeror will
be responsible for the health and daily care of these chimpanzees for the
remainder of the chimpanzee's life. Any Offeror should have the capability to
isolate or appropriately separate most returned chimpanzees from the rest of
their colony since many animals will have been exposed to hepatitis C virus.
The Government shall establish a one time loan fee schedule for the
Government's use of the chimpanzees, and a return fee schedule for the
endowment that will be paid to any Offeror depending on the age and use
history of the chimpanzee being returned.  Any successful contractor will be
free to seek additional sources of income or support for the chimpanzees once
they are returned to their facility by the NIAID.

Any Offeror must have an Office for Protection from Research Risks Assurance
Number and a United States Department of Agriculture R Registration. Any
Offeror must have or be able to obtain a Association for Assessment and
Accreditation of Laboratory Animal Care International file number. The
facility in which the animals are housed shall be operated in compliance with:
a. The Animal Welfare Act (P.L. 89-544, as amended) Rules and Regulations
published in the Code of Federal Regulations (CFR), Title 9 (Animals and
Animal Products), Chapter 1, Subchapter A (Animal Welfare), Parts 1, 2, and 3. 
b. Public Health Service (PHS) Policy on Humane Care and Use of Laboratory
Animals, updated 1996. c. The Guide for the Care and Use of Laboratory
Animals, revised 1996. d. Biosafety in Microbiological and Biomedical
Laboratories (CDC-NIH 1993). e. Occupational Health and Safety in the Care and
Use of Research Animals (NRC 1997). In addition, any Offeror must be able to
document the experience and capabilities of professional and technical
personnel assigned to this project for providing animal care. The professional
and technical personnel shall have extensive experience in non-human primate
medicine and surgery and infectious disease research. The professional staff
will also be evaluated with respect to specialty board certification by the
American College of Laboratory Animal Medicine, advanced degrees, and
residency training in laboratory animal medicine. The technical staff will
also be evaluated with respect to American Association for Laboratory Animal
Science technician certification.

INQUIRIES

Additional information can be obtained by calling the Contracting Officer.
Capability statement may be submitted to: 

Ms. Karin Eddy, Contracting Officer
Acquisitions Management Operations Branch, NIAID
6003 Executive Blvd, Room 1C-38
Bethesda, MD  20892  
Telephone: 301-496-3878


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