INCREASE IN TOTAL COSTS FOR PROGRAM PROJECTS NIH GUIDE, Volume 26, Number 31, September 19, 1997 P.T. Keywords: National Institute of Dental Research The National Institute of Dental Research (NIDR) announces a change in policy regarding program project grants (P01). Currently, in order for a grant to be funded as a P01 it must consist of a minimum of three research projects, not including cores, and the first year direct costs may not exceed $500,000. Grants that include consortium arrangements may exceed the cap by the amount of the indirect costs associated with the consortium. This policy has been in effect for approximately the past five years. During this time the average first year direct costs for investigator-initiated individual research grants (R01) has surpassed, by nearly twenty-five percent, the average costs for a single project which is part of a P01, thus leading to the situation whereby research supported by the P01 mechanism may be at a fiscal disadvantage to that supported by the R01 mechanism. Also, for fiscal planning purposes, the Institute finds it more effective to place limits on maximum levels of funding in terms of total (i.e., direct plus indirect) costs rather than direct costs alone. Therefore, effective immediately, the NIDR modifies its policy and will accept applications for all new (Type 1) and competitively renewed (Type 2) program projects whose total first year costs (i.e., direct plus indirect costs) do not exceed $1.125 million. This represents an increase of approximately one-third and brings the average direct cost of an individual project included in a P01 more in line with the current average direct costs for an R01 funded by the NIDR. While the minimum number of fundable research projects required for a P01 still remains at three, applicants are strongly encouraged to plan research supported through P01s to include a minimum of four fundable projects of high scientific merit. Potential applicants are reminded of the National Institutes of Health (NIH) policy (NIH Guide for Grants and Contracts, Volume 25, Number 14, May 3, 1996) that requires that all applicants receive prior written approval before submitting a formal investigator- initiated Type 1 application whose first year direct costs equal or exceed $500,000. Prior to submitting a P01 or any other grant application with first year direct costs above $500,000, applicants must telephone the extramural scientific program director responsible for the administration of the scientific subject matter of the proposed research. A full listing is available through the NIDR Home Page (http://www.nidr.nih.gov) and applicants are encouraged to review the information about extramural scientific program interests and priorities listed there. For projects of this size, applicants should be prepared to provide the following information to NIDR staff: o Overall objectives and goals of the P01 as a whole. o Specific aims of each research project as it relates to the objectives and goals of the P01. o Overall and individual project/core budgets including any consortium costs. o Names and institutions/departments of affiliation of key personnel. Following review by Institute staff, a written response indicating whether or not the application falls within the programmatic interests of the NIDR will be forwarded to the applicant within 15 working days. INQUIRIES Additional information regarding these policies can be obtained from extramural scientific program directors within the Division of Extramural Research or from Dr. Norman S. Braveman, Assistant Director for Program Development, Division of Extramural Research, National Institute of Dental Research (Telephone: (301) 594-2089; Email: BravemanN@de45.nidr.nih.gov).
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