PLANT COLLECTION AND TAXONOMY NIH GUIDE, Volume 24, Number 29, August 11, 1995 RFP AVAILABLE: NCI-CM-67244-30 P.T. 34 Keywords: Plant Sciences National Cancer Institute The National Cancer Institute (NCI), Division of Cancer Treatment (DCT), Development Therapeutics Program (DTP) anticipates the award of three cost-reimbursement contracts, for a base period of three years, with two one-year option years, beginning on or about September 1, 1996. The objective of this project is to establish contracts for the collection and taxonomy of plants from the following regions designated as follows: Task A: tropical Africa, with emphasis on Madagascar; Task B: Southeast Asia, with emphasis on Papua New Guinea; and Task C: the continental United States of America. The collections will be evaluated as sources of potential antineoplastic and anti-AIDS agents, with the ultimate goal being the discovery of novel structural types that can be developed for the selective treatment of cancer and AIDS in man. Successful offerors will be expected to provide qualified personnel, materials, and equipment for the collection, identification, storage, and shipping of plant samples (500 per year each from Africa and Southeast Asia and 1000 from the United States) to an NCI-designated extraction facility. Collections will comprise approximately 0.3-1.0kg (dry weight) of each sample and each plant will be identified as far as possible at the time of collection. Properly prepared voucher specimens for each plant will be collected for the purposes of unambiguous identification, and for permanent deposition of, at a minimum, two herbaria designated by NCI. The contractor will be expected to provide detailed documentation, including complete identification of each plant collected. The collection team should include a qualified plant taxonomist and personnel experienced in plant collection and identification, and having familiarity with the customs of the local populations. The Principal Investigator should be trained in botany or a related field and should have at least five years of experience in plant collection and identification. It is anticipated that re-collections of up to 10 plants per year in quantities of 10-50 kg will be required starting in the second year of the contract. The number of initial small scale collections will be reduced in proportion to the number and size of the large scale re-collections undertaken. Collections will include species from as wide a variety of families genera as possible. A list of genera with number of species collected in each genus since 1986 will be provided in order to aid in the determination of priorities in the collection program. In the case of trees and large shrubs, samples of plant parts may be collected and stored separately for individual evaluation, with each part being considered equivalent to plant sample. In addition, a list of countries in which collections have been performed and the number of samples collected in each country will be provided. The contractor will be responsible for obtaining all necessary permits including shipping and expert permits from foreign governments and agencies, for delivery of samples and voucher specimens to facilities in the United States. A "Letter of Collection" stating NCI's willingness to collaborate with local scientists and/or authorities in the discovery and development of novel drugs from plants collected will be provided to the contractor. The Government anticipates the award of one contract for each of the regions designated in Task A, B, and C. This is a recompetition of a group of contractors performing similar collections. The Request for Proposal (RFP) will be available on or about August 29, 1995. INQUIRIES A copy of the RFP may be obtained by written request from: Ms. Elsa B Carlton Research Contracts Branch National Cancer Institute Executive Plaza South, Room 603 6120 Executive Boulevard MSC 7220 Bethesda, MD 20892-7220 .
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