MASTER AGREEMENT FOR TUMOR TISSUE RESOURCES FOR EVALUATION OF PROMISINGDIAGNOSTIC AND PROGNOSTIC APPROACHES



NIH GUIDE, Volume 21, Number 13, April 3, 1992



RFP AVAILABLE:  NCI-CB-21001-32



P.T. 34



Keywords:

  Cancer/Carcinogenesis 

  Biological Resources 

  Bioassay 

  Biology, Molecular 



National Cancer Institute



The National Cancer Institute is seeking experienced organizations that

are able to access and provide large numbers of paraffin embedded tumor

tissues (or whenever available, frozen tumor specimens) with associated

patient follow-up data to be used for the validation of promising new

diagnostic and prognostic assays.  The tumor tissue required and the

assays to be performed will be defined by Master Agreement Orders

(MAOs) issued during the period of performance.  The MAOs will be

awarded based upon competition among members of the Master Agreement

(MA) pool.  MA holders selected for award shall provide a minimum

number of paraffin blocks (and/or frozen tissue whenever available) of

breast, colorectal, and/or bladder tumor tissue of specific tumor

stages with a minimum number of years of clinical follow-up.  MA

holders shall perform evaluations of promising new diagnostic and

prognostic techniques as defined by individual MAOs.  Offerors may

qualify to perform one, all, or any combination, of the following

methodologies:  Flow cytometry studies of cell proliferation, molecular

biology studies, and/or immunohistochemical assays.  MAs will be

awarded to all organizations whose technical proposal is considered

acceptable.  Multiple MAOs may be issued in each year.  An MA holder is

free to respond to any particular Request for Proposals (RFP) without

having any affect on its MA.  The proposals will be due by COB May 4,

1992.



Richard L. Hartmann

Contracting Officer's Representative

Research Contracts Branch

Cancer Etiology Contracts Section

National Cancer Institute

Executive Plaza South, Room 620

9000 Rockville Pike

Bethesda, MD  20892

Telephone:  (301) 496-8611



No collect calls will be accepted.



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